This formula yields 20MG of stabilized Sulforaphane per serving, using BroccoRaphanin Broccoli Seed Extract and BroccoPhane, which contain stabilized Sulforaphane and Glucoraphanin.

Sulforaphane has been studied in several clinical studies of Asperger/ASD patients, including children and young adults. The results have been good, with a recent 2020 review of 5 clinical studies saying that: However, more recently (mentioned in her August 2018 crowdcast) she has stopped freezing them, instead opting to put them in the fridge post-harvest. Plants contain chemicals which are used for their self-defense (phytochemicals). Generally, plants evolved these chemicals to be toxic to organisms smaller than humans (for example pathogens). Thus, what may be toxic to a pathogen, has a lesser effect on a human. Ingested in small amounts, some of these phytonutrients exhibit positive effects in humans. But if you consume them at high amounts; they become toxic. This is referred to as hormesis, or, the hormetic effect – and is illustrated by the image below: The 3 supplements above have been tested and used in clinical trials by John Hopkins University – so we can trust they contain what they say, unlike many other broccoli sprout supplements that are ineffective.May improve constipation. In a 4-week study in 48 adults, eating 20 grams of sulforaphane-rich broccoli sprouts improved symptoms of constipation. No effect was found for alfalfa sprouts, which are sulforaphane-free ( 27).

We also looked for products with the myrosinase enzyme needed to convert glucoraphanin to sulforaphane in the small intestine. Potency Sulforaphane can be obtained naturally from a range of cruciferous vegetables. These vegetables not only provide sulforaphane but also many other important vitamins, minerals, and antioxidants. Zhang Z, Atwell LL, Farris PE, Ho E, Shannon J. Associations between cruciferous vegetable intake and selected biomarkers among women scheduled for breast biopsies. Public Health Nutr. 2016;19(7):1288-1295. doi:10.1017/S136898001500244X Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation” published in Oxidative Medicine and Cellular LongevitySo are there any contraindications with sulforaphane and BrocElite? Not that I’m aware of at this point. I do have a few patients that are sensitive to sulfur-based compounds in general, like glutathione or [methylsulfonylmethane], and folks with that issue may want to start with maybe one capsule or half [a] capsule and see how they do and then build up to the full dose. But that’s pretty rare. Otherwise, in more than 2,000 studies, sulforaphane has been safe and well-tolerated at the typical doses found in broccoli sprouts and supplements. I suggest a dose of two capsules per day taken at breakfast. And [there are two] reasons [why] I say breakfast. One, it’s generally better to take it with food. In about 10 to 20 percent of people, it will cause mild gastrointestinal discomfort if they take it on an empty stomach. And that’s been more true in my patients with [small intestinal bacterial overgrowth] or other [gastrointestinal] issues. The second reason I suggest taking it [at] breakfast is that because of how it upregulates BDNF levels, it can really increase mental clarity and focus and have all these amazing benefits. But I’ve found in some of my patients, if you take it right before bed, it can actually interfere with getting to sleep because there’s so much activity; there’s so much going on in the brain. So that can easily be avoided by taking it at breakfast, instead of at dinner, instead of before bed. For those elsewhere, a UK company called Vitality Pro now ships Prostaphane internationally ( product link). Prostaphane is 10 mg per capsule also. The men taking part had broccoli soup once a week for a year. They were put into 1 of 3 groups at random:

In these foods, it’s in the inactive form glucoraphanin that belongs to the glucosinolate family of plant compounds. May protect against sun damage. Studies suggest that sulforaphane may protect against ultraviolet (UV) skin damage caused by the sun ( 21, 22, 23). Each capsule of Solaray Activated Broccoli contains 350 mg of broccoli seed extract (standardized for 10% sulforaphane glucosinolates). Plus, it contains 13 mg of myrosinase and 50 mg of freeze-dried broccoli sprouts. We’ve listed the best products to suit a range of budgets while never skimping on quality. BROQ is the most expensive, while Jarrow Formulas BroccoMax and Double Woods Sulforaphane are more affordable. What is Sulforaphane?That said, there is no conclusive research to confirm this yet. Does Sulforaphane Cause Weight Gain? Another factor to consider is the dosage. The optimal dosage of sulforaphane supplements is not yet clear, but studies have used doses ranging from 10 to 100 milligrams per day. It’s also essential to choose a supplement that is free from additives and fillers.

Setting aside the inconvenience of having to make the sprouts and the issues with sterilizing them, the elephant in the room is that you never know if the broccoli seeds you’re buying actually contain glucoraphanin, and that’s whether you’ll get any sulforaphane when you sprout the seeds or what dose you’ll get if you do. Another reason I like BrocElite is that they add another isothiocyanate to the capsule called phenyl isothiocyanate, or PEITC for short. I honestly think this podcast is going to win the award for acronyms. PEITC is not found in broccoli; it’s found in watercress, and it’s a sort of chemical cousin to sulforaphane. Research suggests that it has a synergistic effect. When it’s combined with sulforaphane, it yields a 30 percent greater activation of Nrf2 than sulforaphane alone.Each bottle contains 60 capsules. The serving size is 2 capsules, so it will last one month. Each serving gives you 20 mg of active sulforaphane. The study found that sulforaphane effectively reduced fasting blood sugar levels by 6.5% and improved hemoglobin A1c, a marker of long-term blood sugar control. These effects were particularly strong in participants who were obese with poor diabetes control ( 17). I take either 20 mg of actual sulforaphane (BROQ supplement, two capsules) or the equivalent of about 18.4 mg (Broccomax supplement, 4 capsules) every day.